Causal Associations of Urate With Cardiovascular Risk Factors: Two-Sample Mendelian Randomization
BackgroundMendelian Randomization (MR) studies show conflicting causal associations of genetically predicted serum urate with cardiovascular risk factors (i.e., hypertension, diabetes, lipid profile, and kidney function). This study aimed to robustly investigate a causal relationship between urate a...
Main Authors: | Thitiya Lukkunaprasit, Sasivimol Rattanasiri, Boonsong Ongphiphadhanakul, Gareth J. McKay, John Attia, Ammarin Thakkinstian |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-07-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2021.687279/full |
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