Confounding factors in vesicle uptake studies using fluorescent lipophilic membrane dyes

Small extracellular vesicles (sEVs) such as exosomes are nanocarriers of proteins, RNAs and DNAs. Isolation of pure sEV populations remains challenging, with reports of protein and lipoprotein contaminants in the isolates. Cellular uptake – a cornerstone for understanding exosome and sEV function –...

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Bibliographic Details
Main Authors: Kaloyan Takov, Derek M. Yellon, Sean M. Davidson
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:http://dx.doi.org/10.1080/20013078.2017.1388731