Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products in humans. However, the clinical use of SV40 vecto...

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Bibliographic Details
Main Authors: Miguel G. Toscano, Jeroen van der Velden, Sybrand van der Werf, Machteld Odijk, Ana Roque, Rafael J. Camacho-Garcia, Irene G. Herrera-Gomez, Irene Mancini, Peter de Haan
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
SV40 viral vectors
SuperVero
SVac
packaging cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117300827

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http://www.sciencedirect.com/science/article/pii/S2329050117300827

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