Autoproteolytic Activation of Bacterial Toxins

Autoproteolytic Activation of Bacterial Toxins

Protease domains within toxins typically act as the primary effector domain within target cells. By contrast, the primary function of the cysteine protease domain (CPD) in Multifunctional Autoprocessing RTX-like (MARTX) and Clostridium sp. glucosylating toxin families is to proteolytically cleave th...

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Bibliographic Details
Main Author: Aimee Shen
Format: Article
Language:English
Published: MDPI AG 2010-05-01
Series:Toxins
Subjects:
cysteine protease domain (CPD)
MARTX toxin
glucosylating toxin (GT)
inositol hexakisphosphate (InsP6)
glucosyltransferase (Glc)
structure activity relationship (SAR)
Online Access:http://www.mdpi.com/2072-6651/2/5/963/

Internet

http://www.mdpi.com/2072-6651/2/5/963/

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