Review on circular RNAs and new insights into their roles in cancer

Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently closed, continuous stable loops without a 5′end cap and 3′end poly(A) tai...

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Bibliographic Details
Main Authors: Xiaozhu Tang, Hongyan Ren, Mengjie Guo, Jinjun Qian, Ye Yang, Chunyan Gu
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021000222