Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis

Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis

Abstract Background The anti-inflammatory effect of glycyrrhizin has been widely recognized, while the specific mechanism of glycyrrhizin in psoriasis remains poorly understood. Results In the imiquimod-induced mouse model of psoriasis (IMD), we found that glycyrrhizin can substantially improve the...

Full description

Bibliographic Details
Main Authors: Huang Qiong, Ling Han, Nanxue Zhang, Huyan Chen, Kexiang Yan, Zhenghua Zhang, Ying Ma, Jinhua Xu
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Immunology
Subjects:
Psoriasis
Glycyrrhizin
IL-17A
SIRT1-STAT3 pathway
Online Access:https://doi.org/10.1186/s12865-021-00421-z

Internet

https://doi.org/10.1186/s12865-021-00421-z

Similar Items