The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.

The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.

Hypercortisolemia has been suggested as a primary hormonal mediator of whole-body catabolism following severe burn injury. Ketoconazole, an anti-fungal agent, inhibits cortisol synthesis. We, therefore, studied the effect of ketoconazole on post-burn cortisol levels and the hyper-catabolic response...

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Bibliographic Details
Main Authors: Marc G Jeschke, Felicia N Williams, Celeste C Finnerty, Noe A Rodriguez, Gabriela A Kulp, Arny Ferrando, William B Norbury, Oscar E Suman, Robert Kraft, Ludwik K Branski, Ahmed M Al-mousawi, David N Herndon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3350497?pdf=render

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http://europepmc.org/articles/PMC3350497?pdf=render

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