Factors Promoting Development of Fibrosis in Crohn’s Disease

The concepts on the pathophysiology of intestinal fibrosis in Crohn’s disease (CD) have changed in recent years. Some years ago fibrosis was regarded to be a consequence of long-standing inflammation with subsequent destruction of the gut wall matrix followed by scar formation and collagen depositio...

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Bibliographic Details
Main Authors: Gerhard Rogler, Martin Hausmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00096/full