An in silico approach reveals associations between genetic and epigenetic factors within regulatory elements in B cells from primary Sjögren’s syndrome patients

An in silico approach reveals associations between genetic and epigenetic factors within regulatory elements in B cells from primary Sjögren’s syndrome patients

Recent advances in genetics have highlighted several regions and candidate genes associated with primary Sjögren's syndrome (SS), a systemic autoimmune epithelitis that combines exocrine gland dysfunctions, and focal lymphocytic infiltrations. In addition to genetic factors, it is now clear tha...

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Bibliographic Details
Main Authors: Orsia D. Konsta, Christelle eLE DANTEC, Amandine eCharras, Wesley H. Brooks, Marina I Arleevskaya, Anne eBordron, Yves eRenaudineau
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Genetics
epigenetics
B cells
Histone Modifications
polymorphism
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00437/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00437/full

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