EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

Background: With the capacity to modulate gene networks in an environmentally-sensitive manner, the role of epigenetic systems in mental disorders has come under intense investigation. Dysregulation of epigenetic effectors, including microRNAs and histone-modifying enzymes, may better explain the ro...

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Bibliographic Details
Main Authors: Andrea L. Johnstone, Jiaqi J. O'Reilly, Annika J. Patel, Zhihong Guo, Nadja S. Andrade, Marco Magistri, Lubov Nathanson, Rustam Esanov, Brooke H. Miller, Gustavo Turecki, Shaun P. Brothers, Zane Zeier, Claes Wahlestedt
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Neurobiology of Disease
Subjects:
miR-132, EZH1, microRNA
Epigenetics
Schizophrenia
Prefrontal cortex
Antipsychotics
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118304194

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http://www.sciencedirect.com/science/article/pii/S0969996118304194

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