The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis

The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis

<p>Abstract</p> <p>Background</p> <p>Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that plays an important role in survival signaling. FAK has been shown to be overexpressed in breast cancer tumors at early stages of tumorigenesis.</p> <p>Met...

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Bibliographic Details
Main Authors: Zhang Li, Zheng Min, Golubovskaya Vita M, Li Jian-Liang, Cance William G
Format: Article
Language:English
Published: BMC 2009-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/280

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http://www.biomedcentral.com/1471-2407/9/280

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