EGFR‐targeted CAR‐T cells are potent and specific in suppressing triple‐negative breast cancer both in vitro and in vivo

EGFR‐targeted CAR‐T cells are potent and specific in suppressing triple‐negative breast cancer both in vitro and in vivo

Abstract Objectives Triple‐negative breast cancer (TNBC) is well known for its strong invasiveness, rapid recurrence and poor prognosis. Immunotherapy, including chimeric antigen receptor‐modified T (CAR‐T) cells, has emerged as a promising tool to treat TNBC. The identification of a specific target...

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Bibliographic Details
Main Authors: Lin Xia, Zao‐zao Zheng, Jun‐yi Liu, Yu‐jie Chen, Jian‐cheng Ding, Ning‐shao Xia, Wen‐xin Luo, Wen Liu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
triple‐negative breast cancer
epidermal growth factor receptor
chimeric antigen receptor‐modified T‐cell
immunotherapy
Online Access:https://doi.org/10.1002/cti2.1135

Internet

https://doi.org/10.1002/cti2.1135

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