Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis.

Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis.

BACKGROUND: An imbalance between overwhelming inflammation and lymphocyte apoptosis is the main cause of high mortality in patients with sepsis. Baicalin, the main active ingredient of the Scutellaria root, exerts anti-inflammatory, anti-apoptotic, and even antibacterial properties in inflammatory a...

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Main Authors: Jiali Zhu, Jiafeng Wang, Ying Sheng, Yun Zou, Lulong Bo, Fei Wang, Jingsheng Lou, Xiaohua Fan, Rui Bao, Youping Wu, Feng Chen, Xiaoming Deng, Jinbao Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3348138?pdf=render

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http://europepmc.org/articles/PMC3348138?pdf=render

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