Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor

Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor

Abstract In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase. However, TNF‐α has been shown to suppress AGT formation in cultured renal proximal tubular cells. We examine...

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Bibliographic Details
Main Authors: Dewan S. A. Majid, Eamonn Mahaffey, Alexander Castillo, Minolfa C. Prieto, L. Gabriel Navar
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Physiological Reports
Subjects:
angiotensin II
angiotensinogen
High salt intake
renal injury
TNF‐α receptors
Online Access:https://doi.org/10.14814/phy2.14990

Internet

https://doi.org/10.14814/phy2.14990

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