Koumine Attenuates Neuroglia Activation and Inflammatory Response to Neuropathic Pain

Despite decades of studies, the currently available drugs largely fail to control neuropathic pain. Koumine—an alkaloidal constituent derived from the medicinal plant Gelsemium elegans Benth.—has been shown to possess analgesic and anti-inflammatory properties; however, the underlying mechanisms rem...

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Bibliographic Details
Main Authors: Gui-Lin Jin, Sai-Di He, Shao-Mei Lin, Li-Mian Hong, Wan-Qing Chen, Ying Xu, Jian Yang, Su-Ping Li, Chang-Xi Yu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2018/9347696