Molecular cloning and characterization of taurocyamine kinase from Clonorchis sinensis: a candidate chemotherapeutic target.

BACKGROUND: Adult Clonorchis sinensis lives in the bile duct and causes endemic clonorchiasis in East Asian countries. Phosphagen kinases (PK) constitute a highly conserved family of enzymes, which play a role in ATP buffering in cells, and are potential targets for chemotherapeutic agents, since va...

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Bibliographic Details
Main Authors: Jing-Ying Xiao, Ji-Yun Lee, Shinji Tokuhiro, Mitsuru Nagataki, Blanca R Jarilla, Haruka Nomura, Tae Im Kim, Sung-Jong Hong, Takeshi Agatsuma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3836730?pdf=render