Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation

Summary: Bone marrow (BM) stromal cells provide the regulatory framework for hematopoiesis and contribute to developmental stage-specific niches, such as those preserving hematopoietic stem cells. Despite advances in our understanding of stromal function, little is known about the transcriptional ch...

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Bibliographic Details
Main Authors: Patrick M. Helbling, Elena Piñeiro-Yáñez, Rahel Gerosa, Steffen Boettcher, Fátima Al-Shahrour, Markus G. Manz, César Nombela-Arrieta
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314755