Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study

Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study

Abstract Background Autism is a neurodevelopmental disorder that is first manifested during early childhood. Postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mGluR5) in cerebellar vermis and prefrontal cortex of individuals with autism. M...

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Bibliographic Details
Main Authors: S. Hossein Fatemi, Dean F. Wong, James R. Brašić, Hiroto Kuwabara, Anil Mathur, Timothy D. Folsom, Suma Jacob, George M. Realmuto, José V. Pardo, Susanne Lee
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Cerebellum & Ataxias
Subjects:
PET
Autism
mGluR5
Cerebellum
Postcentral gyrus
Precuneus
Online Access:http://link.springer.com/article/10.1186/s40673-018-0082-1

Internet

http://link.springer.com/article/10.1186/s40673-018-0082-1

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