The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

Maintenance of energy homeostasis depends on the highly regulated storage and release of triacylglycerol primarily in adipose tissue, and excessive storage is a feature of common metabolic disorders. CIDEA is a lipid droplet (LD)-protein enriched in brown adipocytes promoting the enlargement of LDs,...

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Bibliographic Details
Main Authors: David Barneda, Joan Planas-Iglesias, Maria L Gaspar, Dariush Mohammadyani, Sunil Prasannan, Dirk Dormann, Gil-Soo Han, Stephen A Jesch, George M Carman, Valerian Kagan, Malcolm G Parker, Nicholas T Ktistakis, Judith Klein-Seetharaman, Ann M Dixon, Susan A Henry, Mark Christian
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
lipid droplet
phospholipid
brown adipose tissue
Online Access:https://elifesciences.org/articles/07485

Internet

https://elifesciences.org/articles/07485

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