Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease.

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease.

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue destruction and airflow limitation. Autophagy is a degradative process involving lysosomal turnover of cellular components, though its role...

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Bibliographic Details
Main Authors: Zhi-Hua Chen, Hong Pyo Kim, Frank C Sciurba, Seon-Jin Lee, Carol Feghali-Bostwick, Donna B Stolz, Rajiv Dhir, Rodney J Landreneau, Mathew J Schuchert, Samuel A Yousem, Kiichi Nakahira, Joseph M Pilewski, Janet S Lee, Yingze Zhang, Stefan W Ryter, Augustine M K Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2552992?pdf=render

Internet

http://europepmc.org/articles/PMC2552992?pdf=render

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