Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics.
The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect genes and alleles that lead to resistance. As novel resistance variants are expected to emerge, such sensitivity is expected to decline unless the new variants are de...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-11-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000547 |