Indy mutants: live long and prosper

Indy encodes the fly homologue of a mammalian transporter of di and tricarboxylatecomponents of the Krebs cycle. Reduced expression of fly Indy or two of the C. elegansIndy homologs leads to an increase in life span. Fly and worm tissues that play key roles inintermediary metabolism are also the pla...

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Bibliographic Details
Main Authors: Stewart eFrankel, Blanka eRogina
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00013/full