Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques.

Zika virus (ZIKV) and dengue virus (DENV) are genetically and antigenically related flaviviruses that now co-circulate in much of the tropical and subtropical world. The rapid emergence of ZIKV in the Americas in 2015 and 2016, and its recent associations with Guillain-Barré syndrome, birth defects,...

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Main Authors: Meghan E Breitbach, Christina M Newman, Dawn M Dudley, Laurel M Stewart, Matthew T Aliota, Michelle R Koenig, Phoenix M Shepherd, Keisuke Yamamoto, Chelsea M Crooks, Ginger Young, Matthew R Semler, Andrea M Weiler, Gabrielle L Barry, Holly Heimsath, Emma L Mohr, Jens Eichkoff, Wendy Newton, Eric Peterson, Nancy Schultz-Darken, Sallie R Permar, Hansi Dean, Saverio Capuano, Jorge E Osorio, Thomas C Friedrich, David H O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007766