Effect of body mass index on response to neo-adjuvant therapy in HER2-positive breast cancer: an exploratory analysis of the NeoALTTO trial

Effect of body mass index on response to neo-adjuvant therapy in HER2-positive breast cancer: an exploratory analysis of the NeoALTTO trial

Abstract Background Obesity is a risk factor for breast cancer (BC) development, recurrence, and death. In view of this, we aimed to investigate the clinical value of obesity in BC patients treated with anti-HER2 therapies in the NeoALTTO trial, which randomized 455 patients to neo-adjuvant lapatini...

Full description

Bibliographic Details
Main Authors: Serena Di Cosimo, Luca Porcu, Dominique Agbor-tarh, Saverio Cinieri, Maria Alice Franzoi, Maria Carmen De Santis, Cristina Saura, Jens Huober, Debora Fumagalli, Miguel Izquierdo, Martine Piccart, Maria Grazia Daidone, Evandro de Azambuja
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Breast Cancer Research
Subjects:
Body mass index
Neo-adjuvant treatment
HER2-positive breast cancer
Pathological complete response
Online Access:http://link.springer.com/article/10.1186/s13058-020-01356-w

Internet

http://link.springer.com/article/10.1186/s13058-020-01356-w

Similar Items