Establishment and Characterization of a Tumor Stem Cell-Based Glioblastoma Invasion Model.

AIMS:Glioblastoma is the most frequent and malignant brain tumor. Recurrence is inevitable and most likely connected to tumor invasion and presence of therapy resistant stem-like tumor cells. The aim was therefore to establish and characterize a three-dimensional in vivo-like in vitro model taking i...

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Bibliographic Details
Main Authors: Stine Skov Jensen, Morten Meyer, Stine Asferg Petterson, Bo Halle, Ann Mari Rosager, Charlotte Aaberg-Jessen, Mads Thomassen, Mark Burton, Torben A Kruse, Bjarne Winther Kristensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4959755?pdf=render