Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis.

<h4>Objectives</h4>To determine whether genetic variation within genes related to the Toll-like receptor, inflammasome and interferon-γ pathways contributes to the differences in treatment response to tumour necrosis factor inhibitors (anti-TNF) in patients with rheumatoid arthritis (RA)...

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Bibliographic Details
Main Authors: Jacob Sode, Ulla Vogel, Steffen Bank, Paal Skytt Andersen, Merete Lund Hetland, Henning Locht, Niels H H Heegaard, Vibeke Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0139781