Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans.

Inflammation is now recognized as a major factor contributing to type 2 diabetes (T2D). However, while the mechanisms and consequences associated with white adipose tissue inflammation are well described, very little is known concerning the situation in skeletal muscle. The aim of this study was to...

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Main Authors: David Patsouris, Jingwei-Ji Cao, Guillaume Vial, Amelie Bravard, Etienne Lefai, Annie Durand, Christine Durand, Marie-Agnés Chauvin, Fabienne Laugerette, Cyrille Debard, Marie-Caroline Michalski, Martine Laville, Hubert Vidal, Jennifer Rieusset
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206428?pdf=render