Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several factors including diet, gut microbial flora, drug administration and liver flavin monooxygenase activity. In humans, recent clini...

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Bibliographic Details
Main Authors: Manuel H. Janeiro, María J. Ramírez, Fermin I. Milagro, J. Alfredo Martínez, Maite Solas
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Nutrients
Subjects:
microbiota
gut dysbiosis
cardiovascular disease
neurological disorder
inflammation
antibiotics
Online Access:http://www.mdpi.com/2072-6643/10/10/1398

Internet

http://www.mdpi.com/2072-6643/10/10/1398

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