Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules.

Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules.

Bacterial capsular polysaccharides are virulence factors and are considered T cell-independent antigens. However, the capsular polysaccharide Sp1 from Streptococcus pneumoniae serotype 1 has been shown to activate CD4(+) T cells in a major histocompatibility complex (MHC) class II-dependent manner....

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Main Authors: Tom Li Stephen, Mario Fabri, Laura Groneck, Till A Röhn, Helena Hafke, Nirmal Robinson, Jens Rietdorf, David Schrama, Jürgen C Becker, Georg Plum, Martin Krönke, Harald Kropshofer, Wiltrud M Kalka-Moll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1828696?pdf=render

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http://europepmc.org/articles/PMC1828696?pdf=render

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