Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins

Murine norovirus (MNV) viral protein genome-linked (VPg) manipulates the cell cycle to induce a G0/G1 arrest and gain a beneficial replication environment. All viruses of the norovirus genus encode a VPg protein; however, it is unknown if the G0/G1 arrest induced by MNV VPg is conserved in other mem...

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Bibliographic Details
Main Authors: Alice McSweeney, Colin Davies, Vernon K. Ward
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
VPg
MNV
Online Access:http://www.mdpi.com/1999-4915/11/3/217