Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.

Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.

Initiation, amplitude, duration and termination of transforming growth factor β (TGFβ) signaling via Smad proteins is regulated by post-translational modifications, including phosphorylation, ubiquitination and acetylation. We previously reported that ADP-ribosylation of Smads by poly(ADP-ribose) po...

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Bibliographic Details
Main Authors: Markus Dahl, Varun Maturi, Peter Lönn, Panagiotis Papoutsoglou, Agata Zieba, Michael Vanlandewijck, Lars P van der Heide, Yukihide Watanabe, Ola Söderberg, Michael O Hottiger, Carl-Henrik Heldin, Aristidis Moustakas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136792?pdf=render

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http://europepmc.org/articles/PMC4136792?pdf=render

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