SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

SARS-CoV-2 is highly pathogenic in humans and poses a great threat to public health worldwide. Clinical data shows a disturbed type I interferon (IFN) response during the virus infection. In this study, we discovered that the nucleocapsid (N) protein of SARS-CoV-2 plays an important role in the inhi...

Full description

Bibliographic Details
Main Authors: Keli Chen, Feng Xiao, Dingwen Hu, Weiwei Ge, Mingfu Tian, Wenbiao Wang, Pan Pan, Kailang Wu, Jianguo Wu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
coronavirus disease 2019
COVID-19
severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
nucleocapsid
interferon
Online Access:https://www.mdpi.com/1999-4915/13/1/47

Internet

https://www.mdpi.com/1999-4915/13/1/47

Similar Items