Preferential Interactions and the Effect of Protein PEGylation.

PEGylation is a strategy used by the pharmaceutical industry to prolong systemic circulation of protein drugs, whereas formulation excipients are used for stabilization of proteins during storage. Here we investigate the role of PEGylation in protein stabilization by formulation excipients that pref...

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Bibliographic Details
Main Authors: Louise Stenstrup Holm, Peter W Thulstrup, Marina R Kasimova, Marco van de Weert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4521882?pdf=render