Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors

Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors

Abstract Background Programmed cell death 1 inhibitors have revolutionized therapy for cancer by their outstanding effectiveness. However, they may cause adverse effects, among which inflammatory myopathy is one of the most disabling. To elucidate its mechanism, we analysed muscle biopsies and compa...

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Bibliographic Details
Main Authors: Shiro Matsubara, Morinobu Seki, Shigeaki Suzuki, Takashi Komori, Mikio Takamori
Format: Article
Language:English
Published: BMJ Publishing Group 2019-09-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
PD-1 inhibitor
Adverse effect
Inflammatory myopathy
Tertiary lymphoid organ
Cytotoxic T cell
High endothelial venule
Online Access:http://link.springer.com/article/10.1186/s40425-019-0736-4

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http://link.springer.com/article/10.1186/s40425-019-0736-4

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