Hsp90 Co-chaperones Form Plastic Genetic Networks Adapted to Client Maturation

Summary: Heat shock protein 90 (Hsp90) is a molecular chaperone regulating the activity of diverse client proteins together with a plethora of different co-chaperones. Whether these functionally cooperate has remained enigmatic. We analyze all double mutants of 11 Saccharomyces cerevisiae Hsp90 co-c...

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Bibliographic Details
Main Authors: Maximilian M. Biebl, Maximilian Riedl, Johannes Buchner
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720310482