Expression and Effects of High-Mobility Group Box 1 in Cervical Cancer

Expression and Effects of High-Mobility Group Box 1 in Cervical Cancer

We investigated the significance of high- mobility group box1 (HMGB1) and T-cell-mediated immunity and prognostic value in cervical cancer. HMGB1, forkhead/winged helix transcription factor p3 (Foxp3), IL-2, and IL-10 protein expression was analyzed in 100 cervical tissue samples including cervical...

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Bibliographic Details
Main Authors: Xiaoao Pang, Yao Zhang, Heng Wei, Jing Zhang, Qingshuang Luo, Chenglin Huang, Shulan Zhang
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:International Journal of Molecular Sciences
Subjects:
high-mobility group box 1 protein (HMGB1)
regulatory T cells (Tregs)
cervical cancer
forkhead/winged helix transcription factor p3 (Foxp3)
immunosuppression
serum squamous cell carcinoma antigen (SCC-Ag)
Online Access:http://www.mdpi.com/1422-0067/15/5/8699

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http://www.mdpi.com/1422-0067/15/5/8699

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