Integrated analysis of miRNAs and DNA methylation identifies miR‐132‐3p as a tumor suppressor in lung adenocarcinoma

Integrated analysis of miRNAs and DNA methylation identifies miR‐132‐3p as a tumor suppressor in lung adenocarcinoma

Abstract Background Aberrant miRNA expression and DNA methylation are two major epigenetic events in lung adenocarcinoma (LUAD). We conducted a combined analysis of the molecular changes in LUAD. Methods We analyzed differentially expressed miRNAs and methylated CpG loci in 489 LUAD tissues versus 4...

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Bibliographic Details
Main Authors: Yun Su, Amol Shetty, Feng Jiang
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Thoracic Cancer
Subjects:
DNA methylation
epigenetics
lung cancer
microRNA
Online Access:https://doi.org/10.1111/1759-7714.13497

Internet

https://doi.org/10.1111/1759-7714.13497

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