Mechanism of Follicular Helper T Cell Differentiation Regulated by Transcription Factors

Helping B cells and antibody responses is a major function of CD4+T helper cells. Follicular helper T (Tfh) cells are identified as a subset of CD4+T helper cells, which is specialized in helping B cells in the germinal center reaction. Tfh cells express high levels of CXCR5, PD-1, IL-21, and other...

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Bibliographic Details
Main Authors: Long-Shan Ji, Xue-Hua Sun, Xin Zhang, Zhen-Hua Zhou, Zhuo Yu, Xiao-Jun Zhu, Ling-Ying Huang, Miao Fang, Ya-Ting Gao, Man Li, Yue-Qiu Gao
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2020/1826587