Nonparenchymal fluid is the source of increased mean diffusivity in preclinical Alzheimer's disease

Nonparenchymal fluid is the source of increased mean diffusivity in preclinical Alzheimer's disease

Abstract Introduction Although increased mean diffusivity of the white matter has been repeatedly linked to Alzheimer's disease pathology, the underlying mechanism is not known. Methods Here, we used ADNI‐3 multishell diffusion magnetic resonance imaging data to separate the diffusion signal of...

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Bibliographic Details
Main Authors: Farshid Sepehrband, Ryan P. Cabeen, Giuseppe Barisano, Nasim Sheikh‐Bahaei, Jeiran Choupan, Meng Law, Arthur W. Toga, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Preclinical AD
White matter alteration
White matter fluid
Nonparenchymal fluid
Online Access:https://doi.org/10.1016/j.dadm.2019.03.002

Internet

https://doi.org/10.1016/j.dadm.2019.03.002

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