Transcriptional dysregulation in NIPBL and cohesin mutant human cells.

Transcriptional dysregulation in NIPBL and cohesin mutant human cells.

Cohesin regulates sister chromatid cohesion during the mitotic cell cycle with Nipped-B-Like (NIPBL) facilitating its loading and unloading. In addition to this canonical role, cohesin has also been demonstrated to play a critical role in regulation of gene expression in nondividing cells. Heterozyg...

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Bibliographic Details
Main Authors: Jinglan Liu, Zhe Zhang, Masashige Bando, Takehiko Itoh, Matthew A Deardorff, Dinah Clark, Maninder Kaur, Stephany Tandy, Tatsuro Kondoh, Eric Rappaport, Nancy B Spinner, Hugo Vega, Laird G Jackson, Katsuhiko Shirahige, Ian D Krantz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2680332?pdf=render

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http://europepmc.org/articles/PMC2680332?pdf=render

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