Elucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling.

BACKGROUND: Human skin has the capacity to metabolise foreign chemicals (xenobiotics), but knowledge of the various enzymes involved is incomplete. A broad-based unbiased proteomics approach was used to describe the profile of xenobiotic metabolising enzymes present in human skin and hence indicate...

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Bibliographic Details
Main Authors: Sven van Eijl, Zheying Zhu, John Cupitt, Magdalena Gierula, Christine Götz, Ellen Fritsche, Robert J Edwards
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3406074?pdf=render