Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types

Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types

PRC2 (Polycomb repressive complex 2) is an evolutionarily conserved protein complex required to maintain transcriptional repression. The core PRC2 complex includes EZH2, SUZ12, and EED proteins and methylates histone H3K27. PRC2 is known to contribute to carcinogenesis and several small molecule inh...

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Bibliographic Details
Main Authors: Maksim Erokhin, Olga Chetverina, Balázs Győrffy, Victor V. Tatarskiy, Vladic Mogila, Alexander A. Shtil, Igor B. Roninson, Jerome Moreaux, Pavel Georgiev, Giacomo Cavalli, Darya Chetverina
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
PRC2
EZH2
cancer
oncology
PRC2 inhibitors
EZH2 inhibitors
Online Access:https://www.mdpi.com/2072-6694/13/13/3155

Internet

https://www.mdpi.com/2072-6694/13/13/3155

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