Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial

Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial

ObjectivesEarly treatment of HIV-infected children and adults is important for optimal immune reconstitution. Infants’ immune systems are more plastic and dynamic than older children’s or adults’, and deserve particular attention. This study aimed to understand the response of the HIV-infected infan...

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Bibliographic Details
Main Authors: Joanna Lewis, Helen Payne, A. Sarah Walker, Kennedy Otwombe, Diana M. Gibb, Abdel G. Babiker, Ravindre Panchia, Mark F. Cotton, Avy Violari, Nigel Klein, Robin E. Callard
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
HIV
children
antiretroviral therapy
planned treatment interruption
CD4 T cells
CD4 count
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01162/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01162/full

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