Clustered Protocadherins Emerge as Novel Susceptibility Loci for Mental Disorders

Clustered Protocadherins Emerge as Novel Susceptibility Loci for Mental Disorders

The clustered protocadherins (cPcdhs) are a subfamily of type I single-pass transmembrane cell adhesion molecules predominantly expressed in the brain. Their stochastic and combinatorial expression patterns encode highly diverse neural identity codes which are central for neuronal self-avoidance and...

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Bibliographic Details
Main Authors: Zhilian Jia, Qiang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neuroscience
Subjects:
axonal tiling and myelination
neuronal self-recognition and dendrite self-avoidance
cell adhesion
neuropsychiatric diseases
neuronal connectivity
gene dysregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.587819/full

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https://www.frontiersin.org/articles/10.3389/fnins.2020.587819/full

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