Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target

African swine fever virus (ASFV), an Asfivirus affecting pigs and wild boars with up to 100% case fatality rate, is currently rampaging throughout China and some other countries in Asia. There is an urgent need to develop therapeutic and preventive reagents against the virus. Our crystallographic an...

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Bibliographic Details
Main Authors: Changyao Li, Yan Chai, Hao Song, Changjiang Weng, Jianxun Qi, Yeping Sun, George F. Gao
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.02483-19