No effect of unacylated ghrelin administration on subcutaneous PC3 xenograft growth or metabolic parameters in a Rag1-/- mouse model of metabolic dysfunction.

No effect of unacylated ghrelin administration on subcutaneous PC3 xenograft growth or metabolic parameters in a Rag1-/- mouse model of metabolic dysfunction.

Ghrelin is a peptide hormone which, when acylated, regulates appetite, energy balance and a range of other biological processes. Ghrelin predominately circulates in its unacylated form (unacylated ghrelin; UAG). UAG has a number of functions independent of acylated ghrelin, including modulation of m...

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Bibliographic Details
Main Authors: Michelle L Maugham, Inge Seim, Patrick B Thomas, Gabrielle J Crisp, Esha T Shah, Adrian C Herington, Kristy A Brown, Laura S Gregory, Colleen C Nelson, Penny L Jeffery, Lisa K Chopin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6245673?pdf=render

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http://europepmc.org/articles/PMC6245673?pdf=render

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