Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction

<p>Abstract</p> <p>Background</p> <p>Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the structure and chemistry of the catalytic binding site residues can be l...

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Bibliographic Details
Main Authors: Fofanov Viacheslav Y, Chen Brian Y, Moll Mark, Bryant Drew H, Kavraki Lydia E
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/242