Deciphering the Transcriptomic Heterogeneity of Duodenal Coeliac Disease Biopsies

Deciphering the Transcriptomic Heterogeneity of Duodenal Coeliac Disease Biopsies

Coeliac disease (CD) is a clinically heterogeneous autoimmune disease with variable presentation and progression triggered by gluten intake. Molecular or genetic factors contribute to disease heterogeneity, but the reasons for different outcomes are poorly understood. Transcriptome studies of tissue...

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Bibliographic Details
Main Authors: Johannes Wolf, Edith Willscher, Henry Loeffler-Wirth, Maria Schmidt, Gunter Flemming, Marlen Zurek, Holm H. Uhlig, Norman Händel, Hans Binder
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
molecular subgroups
gene expression signatures
villous atrophy
immune cell de-convolution
machine learning
self-organizing maps
Online Access:https://www.mdpi.com/1422-0067/22/5/2551

Internet

https://www.mdpi.com/1422-0067/22/5/2551

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