TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

The Toll-like receptor (TLR) 7 is a viral sensor for detecting single-stranded ribonucleic acid (ssRNA), the activation of which can induce intracellular innate immunity against viral infections. Imiquimod, a synthetic ligand for TLR7, has been successfully used for the topical treatment of genital/...

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Bibliographic Details
Main Authors: Feng-Zhen Meng, Jin-Biao Liu, Xu Wang, Peng Wang, Wen-Hui Hu, Wei Hou, Wen-Zhe Ho
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biology
Subjects:
Toll-like receptor 7
CC chemokine
macrophages
human immunodeficiency virus
imiquimod
Online Access:https://www.mdpi.com/2079-7737/10/7/661

Internet

https://www.mdpi.com/2079-7737/10/7/661

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