Polyphenol-rich extract of Syzygium cumini leaf dually improves peripheral insulin sensitivity and pancreatic islet function in monosodium L-glutamate-induced obese rats

Polyphenol-rich extract of Syzygium cumini leaf dually improves peripheral insulin sensitivity and pancreatic islet function in monosodium L-glutamate-induced obese rats

Syzygium cumini (L.) Skeels (Myrtaceae) has been traditionally used to treat a number of illnesses. Ethnopharmacological studies have particularly addressed antidiabetic and metabolic-related effects of extracts prepared from its different parts, especially seed and pulp-fruit, however there is a la...

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Bibliographic Details
Main Authors: Jonas Rodrigues Sanches, Lucas Martins França, Vinicyus Teles Chagas, Renato Simões Gaspar, Kayque Almeida dos Santos, Luciana Mateus Gonçalves, Deborah M Sloboda, Alison C Holloway, Everardo Magalhães Carneiro, Ana Paula Gameiro Cappelli, Antonio Marcus de Andrade Paes
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Pharmacology
Subjects:
Hypertriglyceridemia
Insulin Resistance
Obesity
Polyphenols
metabolic syndrome
insulin secretion
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00048/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00048/full

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